Computational Bioengineering Group
Computing Tools and Computational Models

- Back to Model
  Browser Page
- Useful Links
- Direction to Us
- Contact Us
- Back to Home

Computer Modeling of Mitochondrial Tricarboxylic Acid Cycle, Oxidative Phosphorylation, Metabolite Transport, and Electrophysiology

Model Diagram

Illustration of model components

The illustrated components include tricarboxylic acid cycle reactions, oxidative phosphorylation reactions, substrate and cation transport reactions, and passive permeation fluxes. External reactions are not illustrated here. The tricarboxylic acid reactions are numbered 1–11. 1, pyruvate dehydrogenase; 2, citrate synthase; 3, aconitase; 4, isocitrate dehydrogenase; 5, -ketoglutarate dehydrogenase; 6, succinyl-CoA synthetase; 7, succinate dehydrogenase;
8, fumarase; 9, malate dehydrogenase; 10, nucleoside diphosphokinase;
11, glutamate oxaloacetate transaminase.